Publications

Mortuza A., Gahn B., Wharton M., et al. (2026) Current and Historic Levels of Persistent (PAHs, PCBs) and Emerging Pollutant (Nano-Microplastics) Body-Burdens in Oysters and Fish from an Urban-Industrialized Subtropical Estuary (Galveston Bay, TX, USA). Research Square [preprint]. doi: 10.21203/rs.3.rs-9509872/v1

Gahn M. B., Wharton M., Mortuza A., Hala D., Marshall C. D., Kaiser K. (2025) Rapid and Sensitive Quantification of Nano- and Microplastics in Water, Sediment, and Biological Tissue by Pyrolysis-Gas Chromatography Tandem Mass Spectrometry with Dynamic Reaction Monitoring. Analytical Chemistry. doi: 10.1021/acs.analchem.5c05604

Mortuza A., Meese E. N., Wharton M., Gahn B., Petersen L. H., Quigg A., Wells R. J. D., Kaiser K., Hala D. (2025) Comparing persistent (polycyclic aromatic hydrocarbons and polychlorinated biphenyls) and emerging nano(micro)plastics (NMPs) pollutant body-burdens in oysters and fish from Matagorda Bay (Texas, USA). Marine Pollution Bulletin, Vol. 221, 118495. doi: 10.1016/j.marpolbul.2025.118495

Ciesielski M., Hanke M., Jurgens L. J., Kamalanathan M., Mortuza A., Gahn M. B., Hala D., Kaiser K., Quigg A. (2025) A Comparison of Methods to Quantify Nano- and/or Microplastic (NMPs) Deposition in Wild-Caught Eastern Oysters (Crassostrea virginica) Growing in a Heavily Urbanized, Subtropical Estuary (Galveston Bay, USA). Journal of Marine Science and Engineering, 13(11), 2065. doi: 10.3390/jmse13112065

Umeki Y., Nolen R., Hala D., Petersen L. H. (2025) Evaluation of Emerging Contaminants and Biochemical Parameters in the Blood Plasma of Wild American Alligators (Alligator mississippiensis). Environmental Research, 123004. doi: 10.1016/j.envres.2025.123004

Umeki Y., Hala D., Petersen L. H. (2025) Biotransformation of carbamazepine and nicotine in juvenile American alligator (Alligator mississippiensis) in vitro hepatic S9 vs. in situ perfused liver. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, Jan 2025, 287, 110015. doi: 10.1016/j.cbpc.2024.110015

Kopczynski S., Nolen R., Hala D., Lases-Hernández F., Escobedo-Hinojosa W., Arcega-Cabrera F., Oceguera-Vargas I., Quigg A. (2025) Investigation of Anthropogenic and Emerging Contaminants in Sinkholes (Cenotes) of the Great Mayan Aquifer, Yucatán Peninsula. Archives of Environmental Contamination and Toxicology, Vol. 89, 279–299. doi: 10.1007/s00244-025-01149-2

Umeki Y., Hala D., Petersen L. H. (2024) Optimization of an in situ liver perfusion method to evaluate hepatic function of juvenile American alligators (Alligator mississippiensis). Biology Open, Vol. 13, No. 8. doi: 10.1242/bio.060532

Nolen R., Petersen L. H., Kaiser K., Quigg A., Hala D. (2024) Effects of Perfluorooctane Sulfonate (PFOS) Exposure on the Metabolic Physiology of Embryo-larval Zebrafish. Frontiers in Systems Biology, Vol. 4. doi: 10.3389/fsysb.2024.1367562

Nolen R., Prouse A., Russell M. L., Bloodgood J., Clark C. D., Carmichael R. H., Petersen L. H., Kaiser K., Hala D., Quigg A. (2024) Evaluation of fatty acids and carnitine as biomarkers of PFOS exposure in biota (fish and dolphin) from Galveston Bay and the northwestern Gulf of Mexico. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, Vol. 276, 109817. doi: 10.1016/j.cbpc.2023.109817

Kelly E., Petersen L. H., Huggett D., Hala D. (2024) Reaction thermodynamics as a constraint on piscine steroidogenesis flux distributions. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Vol. 287, 111533. doi: 10.1016/j.cbpa.2023.111533

Hala D. (2023) The use of in silico extreme pathway (ExPa) analysis to identify conserved reproductive transcriptional-regulatory networks in humans, mice, and zebrafish. Systems Biology in Reproductive Medicine, Vol. 6, 1–17. doi: 10.1080/19396368.2023.2188996

Faulkner P., Hala D., Shimskie J., Johnson R., Schneider A., Cubbage T., Lozano N., Petersen L. H. (2023) Juvenile American alligators (Alligator mississippiensis) use behavioral thermoregulation to cope with dehydration and salt-loading when chronically exposed to 12‰ saltwater. Animal Behavior and Cognition, Vol. 10, No. 1, 1–13. doi: 10.26451/abc.10.01.01.2023

Simons K., Thibault O., Nolen R., Umeki Y., Faulkner P., Petersen L., Hala D. (2022) A systems toxicological analysis of oxybenzone effects on the metabolic physiology of embryo-larval zebrafish (Danio rerio). Environmental Advances. doi: 10.1016/j.envadv.2022.100308

Kamalanathan M., Mapes S., Prouse A., Faulkner P., Klobusnik N. H., Hillhouse J., Hala D., Quigg A. (2022) Core metabolism plasticity in phytoplankton: Response of Dunaliella tertiolecta to oil exposure. Journal of Phycology. doi: 10.1111/jpy.13286

Nolen R. M., Faulkner P., Ross A. D., Kaiser K., Quigg A., Hala D. (2022) PFASs pollution in Galveston Bay surface waters and biota (shellfish and fish) following AFFFs use during the ITC fire at Deer Park (March 17th–20th 2019), Houston, TX. Science of the Total Environment, Vol. 805, 150361.

Hala D., Petersen L. H., Huggett D. B., Puchowicz M. A., Brunengraber H., Zhang G-F. (2021) Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats. International Journal of Molecular Sciences, Vol. 22, No. 24, 13489. doi: 10.3390/ijms222413489

Kamalanathan M., Mapes S., Hillhouse J., Claflin N., Leleux J., Hala D., Quigg A. (2021) Molecular mechanism of oil induced growth inhibition in diatoms using Thalassiosira pseudonana as the model diatom species. Scientific Reports, Vol. 11, 19831.

Faulkner P., Elsey R. M., Hala D., Petersen L. H. (2021) Correlations between environmental salinity levels, blood biochemistry parameters, and steroid hormones in wild juvenile American alligators (Alligator mississippiensis). Scientific Reports, Vol. 11, 15168.

Hala D., Faulkner P., He K., Kamalanathan M., Brink M., Simons K., Apaydin M., Hernout B., Petersen L. H., Ivanov I., Qian X. (2021) An integrated in vivo and in silico analysis of the metabolism disrupting effects of CPI-613 on embryo-larval zebrafish (Danio rerio). Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, Vol. 248, 109084.

Plumlee J. D., Hala D., Rooker J. R., Shipley J. B., Wells R. J. D. (2021) Trophic ecology of fishes associated with artificial reefs assessed using multiple biomarkers. Hydrobiologia. doi: 10.1007/s10750-021-04647-1

Thibault O., Cubbage T., Brink M., McCarthy J., Gunn C., Torres I., Faulkner P. C., Hala D., Petersen L. H. (2021) The pharmaceutical prednisone affects sheepshead minnow (Cyprinodon variegatus) metabolism and swimming performance. Comparative Biochemistry and Physiology Part A, Vol. 253, 110851.

Lawson M. C., Cullen J. A., Nunnally C. C., Rowe G. T., Hala D. (2020) PAH and PCB body burdens in epibenthic deep-sea invertebrates from the northern Gulf of Mexico. Marine Pollution Bulletin, 1–9.

Ross A. D., Hotard A., Kamalanathan M., Nolen R., Hala D., Clay L. A., Kaiser K., Quigg A. (2020) Awareness is not enough: frequent use of water pollution information and changes to risky behavior. Sustainability, Vol. 12, 8695. doi: 10.3390/su12208695

Bacosa H. P., Kamalanathan M., Cullen J., Shi D., Xu C., Schwehr K. A., Hala D., Wade T. L., Knap A. H., Santschi P. H., Quigg A. (2020) Marine snow aggregates are enriched in polycyclic aromatic hydrocarbons (PAHs) in oil contaminated waters: insights from a mesocosm study. Journal of Marine Science and Engineering, Vol. 8, No. 781. doi: 10.3390/jmse8100781

Hernout B., Leleux J., Lynch J., Ramaswamy K., Faulkner P., Matich P., Hala D. (2020) The integration of fatty acid biomarkers of trophic ecology with pollutant body-burdens of PAHs and PCBs in four species of fish from Sabine Lake, Texas. Environmental Advances, 100001.

Steichen J. L., Labonté J. M., Windham R., Hala D., Kaiser K., Setta S., Faulkner P., Bacosa H., Yan G., Kamalanathan M., Quigg A. (2020) Microbial, physical, and chemical changes in Galveston Bay following an extreme flooding event, Hurricane Harvey. Frontiers in Marine Science, 7, 1–21.

Bacosa H., Steichen J., Kamalanathan M., Windham R., Lubguban A., Labonté J., Kaiser K., Hala D., Santschi P., Quigg A. (2020) Polycyclic aromatic hydrocarbons (PAHs) and putative PAH-degrading bacteria in Galveston Bay, TX (USA), following Hurricane Harvey (2017). Environmental Science and Pollution Research. doi: 10.1007/s11356-020-09754-5

Faulkner P. C., Hala D., Rahman M. S., Petersen L. H. (2019) Short-term exposure to 12‰ brackish water has significant effects on the endocrine physiology of juvenile American alligator (Alligator mississippiensis). Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Vol. 236, 110531. doi: 10.1016/j.cbpa.2019.110531

Cullen J. A., Marshall C., Hala D. (2019) Integration of multi-tissue PAH and PCB burdens with biomarker activity in three coastal shark species from the northwestern Gulf of Mexico. Science of the Total Environment, Vol. 650, 1158–1172.

Hala D., Cullen J. A., Hernout B., Ivanov I. (2018) In silico predicted transcriptional regulatory control of steroidogenesis in spawning female fathead minnows (Pimephales promelas). Journal of Theoretical Biology, Vol. 455, 179–190.

Faulkner P. C., Burleson M. L., Simonitis L., Marshall C. D., Hala D., Petersen L. H. (2018) Effects of chronic exposure to 12‰ saltwater on the endocrine physiology of juvenile American alligator (Alligator mississippiensis). Journal of Experimental Biology, jeb181172. doi: 10.1242/jeb.181172

Bacosa H., Kamalanathan M., Chiu M-H., Tsai S-M., Sun L., Labonte J., Schwehr K. A., Hala D., Santschi P. H., Chin W-C., Quigg A. (2018) Extracellular polymeric substances (EPS) producing and hydrocarbon degrading bacteria isolated from the northern Gulf of Mexico. PLOS ONE, Vol. 13, No. 12, e0208406.

Hala D. (2017) In silico predicted reproductive endocrine transcriptional regulatory networks during zebrafish (Danio rerio) development. Journal of Theoretical Biology, Vol. 417, 51–60. doi: 10.1016/j.jtbi.2017.01.027

Carty D., Hala D., Huggett D. B. (2017) The effects of sertraline on fathead minnow (Pimephales promelas) growth and steroidogenesis. Bulletin of Environmental Contamination and Toxicology, Vol. 98, 753–757. doi: 10.1007/s00128-017-2079-5

Hala D., Petersen L. H., Martinović D., Huggett D. B. (2015) Constraints-based flux balance analysis of perturbed steroidogenesis and gonad growth in fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol. Systems Biology in Reproductive Medicine, Vol. 61, No. 3, 122–138.

Petersen L. H., Hala D., Carty D., Cantu M., Martinović D., Huggett D. B. (2015) Effects of progesterone and norethindrone on female fathead minnow (Pimephales promelas) steroidogenesis. Environmental Toxicology and Chemistry, Vol. 34, No. 2, 379–390.

Hala D., Huggett D. B. (2014) In silico predicted structural and functional robustness of piscine steroidogenesis. Journal of Theoretical Biology, Vol. 345, 99–108. doi: 10.1016/j.jtbi.2013.12.003

Overturf M., Overturf C., Carty D., Hala D., Huggett D. B. (2014) Levonorgestrel exposure to fathead minnows (Pimephales promelas) alters survival, growth, steroidogenic gene expression and hormone production. Aquatic Toxicology, Vol. 148, 152–161.

Thiele I., Swainston N., Fleming R., Hoppe A., et al. incl. Hala D., Palsson B. (2013) A community-generated reconstruction of the human metabolic network and its use for the analysis of omics data. Nature Biotechnology, Vol. 31, 419–425.

Scrimshaw M., Hala D., Okiemute A., Cartmell E., Lester J. (2013) Removal processes for tributyltin during municipal wastewater treatment. Water, Air, & Soil Pollution. doi: 10.1007/s11270-012-1400-5

Hala D., Huggett D. B., Burggren W. W. (2012) Environmental stressors and the epigenome. Drug Discovery Today: Technologies. doi: 10.1016/j.ddtec.2012.05.004

Hala D., Petersen L. H., Martinović D., Huggett D. B. (2012) Constraints-based stoichiometric analysis of hypoxic stress on steroidogenesis in fathead minnows (Pimephales promelas). Journal of Experimental Biology, Vol. 215, 1753–1765.

Overturf M. D., Overturf C. L., Baxter D., Hala D. N., Constantine L., Venables B., Huggett D. B. (2012) Early life-stage toxicity of eight pharmaceuticals to the fathead minnow, Pimephales promelas. Archives of Environmental Contamination and Toxicology, Vol. 62, No. 3, 455–464.

Hala D., Overturf M. D., Petersen L. H., Huggett D. B. (2011) Quantification of 2-hydrazinopyridine derivatized steroid hormones in fathead minnow (Pimephales promelas) blood plasma using LC-ESI⁺/MS/MS. Journal of Chromatography B, Vol. 879, 591–598.

Hala D., Amin A., Mikler A., Huggett D. B. (2010) A constraint-based stoichiometric model of the steroidogenic network of zebrafish (Danio rerio). Journal of Biological Systems, Vol. 18, 669–685.

Hala D., Bristeau S., Dagnac T., Jobling S. (2010) The unexpected sources of organotin contamination in aquatic toxicological laboratory studies. Aquatic Toxicology, Vol. 96, 314–318. doi: 10.1016/j.aquatox.2009.11.015

Hala D., Van Look K., Holt W., Jobling S. (2009) Validation of a method for measuring sperm quality and quantity in reproductive toxicity with pair-breeding male fathead minnows (Pimephales promelas). Institute of Laboratory Animal Research, Vol. 50, No. 4, E1–10.

Ziolko D., Hala D., Lester J., Scrimshaw M. (2009) The effectiveness of conventional trickling filter treatment plants at reducing concentrations of copper in wastewaters. Science of the Total Environment, Vol. 407, 6235–6241.

Runnalls T., Hala D., Sumpter J. (2007) Preliminary studies into the effects of the human pharmaceutical clofibric acid on sperm parameters in adult fathead minnow. Aquatic Toxicology, Vol. 84, No. 1, 111–118.

Schulte-Oehlmann U., Albanis T., Allera A., Bachmann J., Berntsson P., et al. incl. Hala D., Jobling S. (2006) COMPRENDO: focus and approach. Environmental Health Perspectives, Vol. 114, 98–100.